Brazil Built the World's First Single-Dose Dengue Vaccine. Now Comes the Hard Part.
After a 2024 epidemic that infected 6.4 million Brazilians, the Butantan Institute is rolling out a vaccine sixteen years in the making — one shot, all four dengue strains, developed almost entirely on Brazilian soil. Early results are striking: cases are down 94% so far this year. But monitoring the vaccine in millions of real-world arms is now revealing things a decade of clinical trials couldn't.
By Fernanda Souza|15 hours ago